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KMID : 1134820150440020281
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Journal of the Korean Society of Food Science and Nutrition
2015 Volume.44 No. 2 p.281 ~ p.286
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Radical Scavenging and Anti-Obesity Effects of 50% Ethanol Extract from Fermented Curcuma longa L
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Kim Ji-Hye
Jun Woo-Jin
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Abstract
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In this study, free radical scavenging activities (ABTS, DPPH, NBT, TBARS, and ORAC) and anti-obesity potential were evaluated using 50% ethanol extract from fermented Curcuma longa L. (FCE50). FCE50 showed free radical scavenging activities and anti-oxidant potential. Lipid accumulation and intracellular TG content were significantly reduced by 25.8% and 28.6%, respectively, by 250 μg/mL of FCE50 compared to adipocytes. Glucose uptake was significantly reduced by 12.0%. FCE50 significantly reduced mRNA expression of acetyl-CoA carboxylase in 3T3-L1 cells. These results indicate that the anti-adipogenic effect of FCE50 might be due to its radical scavenging activity and anti-oxidant potential.
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KEYWORD
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turmeric, fermented Curcuma longa L., radical scavenging activity, anti-obesity
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